Flower cell or cloverleaf cell

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Flower cell or Cloverleaf cell: They are generally large and very pleomorphic cells. Nuclei are often polylobate; their shape resembles a flower or a cloverleaf. Some nuclei have condensed chromatin while others have a diffuse chromatin pattern. Some cells are nucleolated. There is a variable amount of cytoplasm, which may be pale basophilic to ground glass. Significance: These cells are often seen in T cell lymphoma/leukemia cases. Less commonly, they are observed in B cell lymphoma/leukemia cases also. We express our sincere gratitude to Dr. Divyesh Kothari for his contribution in this.

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