Hyper-segmented neutrophils

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Neutrophil hyper segmentation can be defined as the presence of neutrophils whose nuclei have six or more lobes or the presence of more than 3% of neutrophils with at least five nuclear lobes. The presence of hyper segmented neutrophils is an imperative and explicit diagnostic feature of megaloblastic anemias caused due to deficiency of vitamin B12 & folic acid. Special thanks to Dr. Rekha Radhesh for her participation in this.