Sezary cells

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Sezary Cells also called as Lutzner cells are atypical small to medium sized Lymphoid cells with high nucleus to cytoplasm ratio, hyper convoluted complex folded cerebriform nuclei and are seen abundant in Sezary syndrome. Sezary syndrome (SS) is defined by the triad of erythroderma, generalized lymphadenopathy, and the presence of clonally related neoplastic T cells (Sezary cells) in skin, lymph nodes, and peripheral blood. Special thanks to Dr. Shashi Bansal for her contribution in this.