Tear Drop cell

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Teardrop erythrocytes are poikilocytes that a variable blunt rounded side and a thinning leaking tip, like a tear and play a key role in the evaluation of peripheral blood smears in patients with anemia, especially as part of the “leucoerythroblastic picture”. It can also be an expression of myelofibrosis and extramedullary hematopoiesis (EMH). In healthy subjects, in reactive inflammatory conditions and in anemia of chronic disease (ACD) teardrop cells are thought to form because of the removal of an inclusion from the cell as it moves through the spleen. Special thanks to Dr. Rani Radhakrishnan for contribution in this.